货号：E-2024063260
CAS：29741-09-1
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A726505
Chemical Name:Apigenin 7-Glucuronide
Synonyms:β-D-5-Hydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-glucopyranosiduronic Acid; Apigenin 7-O-Glucuronide; Apigenin 7-O-β-D-Glucuronide; Apigenin 7-O-β-D-Glucuronopyranoside; Apigenin 7-O-β-Glucuronide; Apigenin 7-Glucuronide; Apigenin 7-β-Glucuronide; Apigenin-7-O-β-D Glucuronoside; Scutellarin A
CAS Number:29741-09-1
Molecular Formula:C₂₁H₁₈O₁₁
Appearance:Brown to Dark Brown Solid
Melting Point:>150°C (dec.)
Molecular Weight:446.36
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Food;
Applications:Apigenin 7-Glucuronide is a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.
References:Chaumontet, C., et al.: Carcinogenesis, 15, 2325 (1994), Sato, F., et al.: Biochem. Biophys. Res. Commun., 204, 578 (1994), Kuo, M.L. et al.: Biochem. Biophys. Res. Commun., 212, 767 (1995)
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