货号：E-2024063322
CAS：172673-23-3
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A729825
Chemical Name:Aprepitant N-Oxide
Synonyms:[2R-[2α(R*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-oxido-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
CAS Number:172673-23-3
Molecular Formula:C₂₃H₂₁F₇N₄O₄
Appearance:White to Off-White Solid
Melting Point:>133°C (dec.)
Molecular Weight:550.43
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Aprepitant N-Oxide is an impurity of Fosaprepitant (F727300), a selective neurokinin-1 (NK-1) receptor antahonist. Fosaprepitant is an antiemetic drug, a Aprepitant (A729800) prodrug.
References:Tattersall, F., et al.: Neuropharmacol., 39, 652 (2000), Cocquyt, V., et al.: Eur. J. Canc., 37, 835 (2001),
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