货号：DT2025062141
CAS：2408131-71-3
规格：mg(更多包装需求请咨询客服)
纯度：≥98%
生产商：试剂家

生物活性：Bempedoic acid-d5 is the deuterium labeled Bempedoic acid[1]. Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor[1]. Bempedoic acid (ETC-1002) activates AMPK[2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
Bempedoic acid-d5 相关抗体:
AMPK alpha Antibody
Phospho-AMPK alpha 2 (Thr172) Antibody
AMPK alpha 2 Antibody (YA833)
Phospho-AMPK alpha 2(Ser345) Antibody
AMPK alpha 1 Antibody
AMPK alpha 1 Antibody (YA624)
ATP citrate lyase Antibody
Phospho-AMPK alpha 1 (Ser496) Antibody (YA226)
Phospho-Hormone sensitive lipase (Ser853) Antibody
ATF4 Antibody (YA605)
AMPK alpha 2 Antibody (YA623)
AMPK beta 1 Antibody
AMPK gamma 1 Antibody
ATF4 Antibody
ATP Citrate Lyase Antibody (YA829)
Phospho-AMPK alpha 1 (Ser496) Antibody
MARK2 Antibody (YA2104)
MARK3 Antibody (YA2150)
Phospho-Hormone Sensitive Lipase (Ser855) Antibody (YA2599)
分子量：349.52
Formula：C19H31D5O5
CAS 号：2408131-71-3
非标记 CAS：738606-46-7
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (522 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
 [Content Brief]
[2]. Pinkosky SL, et al. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan;54(1):134-51.
 [Content Brief]
[3]. Filippov S, et al. ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK. J Lipid Res. 2013 Aug54(8):2095-108.
 [Content Brief]