货号：E-T202508210001
CAS：N/A
规格：mg
纯度：≥95%
生产商：试剂家

生物活性：β-Amyloid-15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
β-Amyloid-15N (1-42), human TFA 相关抗体:
RAGE Antibody
PMP70 Antibody (YA1628)
Amyloid Precursor Protein Antibody (YA1130)
Serum Amyloid A Antibody (YA1168)
DISC1 Antibody (YA2430)
Phospho-Amyloid Precursor Protein (Thr743) Antibody (YA2568)
APLP2 Antibody (YA2722)
LRRC15 Antibody (YA3182)
Mint3 Antibody (YA3242)
分子量：4515.10 (free acid)
Formula：C203H311N5415NO60S.xC2HF3O2
非标记 CAS：107761-42-2
Sequence
Asp-Ala-{Glu-15N}-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala (TFA)
Sequence Shortening
DA-{Glu-15N}-FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (543 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Solntseva EI, et al. Impact of amyloid-β peptide (1-42) on voltage-gated ion currents in molluscan neurons. Bull Exp Biol Med. 2011 Oct;151(6):671-4.
 [Content Brief]
[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
 [Content Brief]