货号：E-T202508210001
CAS：N/A
规格：mg
纯度：≥95%
生产商：试剂家

生物活性：Cobimetinib-13C6 (GDC-0973-13C6; XL518-13C6) racemate is the deuterium labeled Cobimetinib (racemate) (HY-13078)[1]. Cobimetinib racemate (GDC-0973 racemate; XL518 racemate) is the racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor[2].
体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
Cobimetinib-13C6 racemate 相关抗体:
MEK1/2 Antibody
Phospho-MEK1 (Ser298) Antibody
MEK1 Antibody
Phospho-MEK4 (Ser80) Antibody
MEK7 Antibody (YA2647)
MEK2 Antibody (YA3059)
MEK5 Antibody (YA3140)
MEK3 Antibody (YA3214)
MEK3/MEK6 Antibody (YA3323)
分子量：537.27
Formula：C1513C6H21F3IN3O2
非标记 CAS：934662-91-6
中文名称：考比替尼 (外消旋体)-13C6
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (535 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
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