货号：E-T202508210001
CAS：N/A
规格：mg
纯度：≥95%
生产商：试剂家

生物活性：2'-Deoxyadenosine monohydrate-2′-13C is the 13C labeled 2'-Deoxyadenosine monohydrate(HY-W011683)[1]. 2′-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. 2′-Deoxyadenosine monohydrate inhibits glucose-stimulated increases seen in islet cyclic AMP (cAMP) accumulation. 2'-Deoxyadenosine monohydrate activates caspase-3 and promotes apoptosis. 2'-Deoxyadenosine monohydrate inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). 2'-Deoxyadenosine monohydrate inhibits the growth of various cells. 2'-Deoxyadenosine monohydrate has an anticancer effect on colon cancer[2][3][4].
体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
2'-Deoxyadenosine monohydrate-2′-13C 相关抗体:
Cleaved-Caspase 9 Antibody
BNSP Antibody
FACL4 Antibody
BrdU Antibody (YA578)
ERK1/2 Antibody
E-Cadherin Antibody (YA470)
Fatty Acid Synthase Antibody (YA766)
DYKDDDDK Tag (FLAG) Antibody
GAPDH Antibody
GFP Antibody
p53 Antibody (YA250)
RUNX2 Antibody
Cleaved-Caspase 1 Antibody
Cleaved-Caspase 3 p12 Antibody
Ferritin Heavy Chain Antibody
Glucose 6 Phosphate Dehydrogenase Antibody
Caspase-3 Antibody
Caspase-9 Antibody
COX2 Antibody
Ctip2 Antibody
Cyclin D1 Antibody (YA485)
Cytochrome C Antibody
METTL3 Antibody
Caspase 7 Antibody
c-Myc Antibody
Cyclin E1 Antibody
TSG101 Antibody
AIF Antibody (YA636)
ALIX Antibody
Alkaline Phosphatase Antibody
分子量：270.25
Formula：C913CH15N5O4
非标记 CAS：16373-93-6
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (548 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
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[2]. Iain L. Campbell, et al. Effects of adenosine, 2-deoxyadenosine and N6-phenylisopropyladenosine on rat islet function and metabolism. Biochem J (1982) 204 (3): 689-696.
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[3]. Giannecchini M, et al. 2'-Deoxyadenosine causes apoptotic cell death in a human colon carcinoma cell line. J Biochem Mol Toxicol. 2003;17(6):329-37.
 [Content Brief]
[4]. Cass CE, et al. Effects of 2'-deoxyadenosine, 9-beta-D-arabinofuranosyladenine, and related compounds on S-adenosyl-L-homocysteine hydrolase activity in synchronous and asynchronous cultured cells. Cancer Res. 1982 Dec;42(12):4991-8.
 [Content Brief]